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The symptoms are nasty, to say the least-- explosive diarrhea, nausea, vomiting, muscle aches, debilitating fatigue.
One might want to take leave of a companion and even rush outdoors to vomit not because they are crude, dim or nasty but because they have revealed themselves to be undeniably and conspicuously nice.
Like, scientists in China recently used CRISPR to make a subgenic modification in wheat — they turned off three genes that repress the wheat’s immune response to a nasty fungal infection.